The FHS also has expanded to include diverse populations so that risk factors in these different groups can be understood.Researchers recognized the need to establish a new study reflecting Framingham’s more diverse communities. Objective: The frequency of coronary heart disease (CHD) and stroke are increased in systemic lupus erythematosus (SLE), but the extent of the increase is uncertain.
A more useful metric is to consider the effects of treatment. the «Adult Treatment Panel III», an expert panel of the National Heart, Lung, and Blood Institute, which is part of the National Institutes of Health (NIH), USA. In the past half century, the study has produced approximately 3,000 articles in leading medical journals. When it launched in 1948 the original goal of the Framingham Heart Study (FHS) was to identify common factors or characteristics that contribute to cardiovascular disease. If a group of 100 persons all have a 20% ten-year risk of cardiovascular disease it means that we should expect that 20 of these 100 individuals will develop cardiovascular disease (coronary heart disease or stroke) in the next 10 years and eighty of them will not develop cardiovascular disease in the next 10 years.It is important to recognize that the strongest predictor of cardiovascular risk in any risk equation is age. Findings such as these pave the way for new interventions to preempt, prevent, or treat these conditions more effectively.The NHLBI has a long history of supporting large population and epidemiology studies that have transformed the way the public approaches heart disease. For this reason, cardiovascular risk scores are used to determine who should be offered preventive drugs such as drugs to lower blood pressure and drugs to lower cholesterol levels.The first Framingham Risk Score included age, sex, LDL cholesterol, HDL cholesterol, blood pressure (and also whether the patient is treated or not for his/her hypertension), diabetes, and smoking. NHLBI has continued to leverage FHS resources to spur new scientific discovery through data sharing.
The researchers then turned their attention to risk factors. It has grown into an ongoing, longitudinal study gathering prospective data on a wide variety of biological and lifestyle risk factors and on cardiovascular, neurological and other types …
It is why, in routine physicals, doctors check for high blood pressure, high cholesterol, unhealthy eating patterns, smoking, physical inactivity, or unhealthy weight. The Framingham Study further reported risk equations linking common risk factors to both coronary heart disease, stroke, and overall fatal and non-fatal cardiovascular disease (CVD) (7,8). You can discover more about this heart disease scoring system and about all the cardiovascular risk factors involved below the form. Researchers also know that these conditions can affect people differently depending on a patient’s sex or race. In April 2002, the study entered a new phase: the enrollment of a third generation of participants, the grandchildren of the original cohort.Since its early days, the FHS has been committed to data sharing. Framingham Heart Study, long-term research project developed to identify risk factors of cardiovascular disease, the findings of which had far-reaching impacts on medicine. Cardiology professionals refer to such patients as having a CHD risk equivalent. Framingham Study is a population-based, observational cohort study that was initiated by the United States Public Health Service in 1948 to prospectively investigate the epidemiology and risk factors for cardiovascular disease. Over the years, careful monitoring of the Framingham study population has led to the identification of the major CVD risk factors – high blood pressure, high blood cholesterol, smoking, obesity, diabetes, and physical inactivity – as well as a great deal of valuable information on the effects of related factors, such as blood triglyceride and high-density lipoprotein cholesterol levels, age, gender, and psychosocial issues.
In 1968, the FHS made massive data tables of FHS-collected measures freely available to outside researchers, many of whom lacked computing resources. Here are a few of the major findings from the FHS:This research has contributed transformative discoveries related to the treatment of heart disease. This was for the first round of extensive physical examinations and lifestyle interviews they would later analyze for common patterns related to cardiovascular disease development.
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